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In vitro and in vivo evaluation of transdermal iontophoretic delivery of hydromorphone

โœ Scribed by R.V. Padmanabhan; J.B. Phipps; G.A. Lattin; R.J. Sawchuk


Book ID
119133929
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
850 KB
Volume
11
Category
Article
ISSN
0168-3659

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Transdermal iontophoretic delivery of tr
โœ Schuetz, Yannic B. (author);Naik, Aarti (author);Guy, Richard H. (author);Vuarid ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons Inc. ๐ŸŒ English โš– 124 KB

The feasibility of delivering triptorelin ]LHRH) by transdermal iontophoresis was evaluated in vitro. Peptide electrotransport at different current densities and donor concentrations was measured across porcine ear skin. The concomitant delivery of an electroosmotic marker enabled calculation of the