✦ LIBER ✦

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

✍ Scribed by Wiemels, J. L.

Book ID: 111950938
Publisher: American Society of Hematology
Year: 2002
Tongue: English
Weight: 202 KB
Volume: 99
Category: Article
ISSN: 0006-4971
DOI: 10.1182/blood.v99.10.3801

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Characterization of the ETO and AML1–ETO

Characterization of the ETO and AML1–ETO proteins involved in the 8;21 translocation in acute myelogenous leukemia

✍ Xiao-Feng Le; David Claxton; Steve Kornblau; You-Hong Fan; Zhao-Mei Mu; Kun-Sang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 997 KB

Simple variant t(8;21) acute myeloid leu

Simple variant t(8;21) acute myeloid leukemias harbor insertions of the AML1 or ETO genes

✍ Sylvie Taviaux; Véronique Brunel; Madeleine Dupont; Francisca Fernandez; Concepc 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

We report on the molecular characterization of two acute myeloid leukemias (AML), one AML-M1 (patient 1) and one AML-M2 (patient 2) with t(8;21)(p21;q22) and t(8;20)(q22;p13), respectively, at diagnosis. The locations of the breakpoints, 21q22 in patient 1 and 8q22 in patient 2, prompted us to searc

AML1-ETO targets and suppresses cathepsi

AML1-ETO targets and suppresses cathepsin G, a serine protease, which is able to degrade AML1-ETO in t(8;21) acute myeloid leukemia

✍ Jin, W; Wu, K; Li, Y-Z; Yang, W-T; Zou, B; Zhang, F; Zhang, J; Wang, K-K 📂 Article 📅 2012 🏛 Nature Publishing Group 🌐 English ⚖ 659 KB

Variant t(8;18;21) translocation in acut

Variant t(8;18;21) translocation in acute myeloid leukemia

✍ Hiroyuki Uchida; Kazuma Ohyashiki; Keisuke Toyama; Michi Kondo; Hisao Ito; Akira 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 205 KB

A novel exon in AML1-ETO negatively infl

A novel exon in AML1-ETO negatively influences the clonogenic potential of the t(8;21) in acute myeloid leukemia

✍ Mannari, D; Gascoyne, D; Dunne, J; Chaplin, T; Young, B 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 296 KB

AML1–ETO downregulates the granulocytic

AML1–ETO downregulates the granulocytic differentiation factor C/EBPα in t(8;21) myeloid leukemia

✍ Pabst, Thomas; Mueller, Beatrice U.; Harakawa, Nari; Schoch, Claudia; Haferlach, 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 845 KB