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Characterization of the ETO and AML1–ETO proteins involved in the 8;21 translocation in acute myelogenous leukemia

✍ Scribed by Xiao-Feng Le; David Claxton; Steve Kornblau; You-Hong Fan; Zhao-Mei Mu; Kun-Sang Chang


Book ID
114792382
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
997 KB
Volume
60
Category
Article
ISSN
0902-4441

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Simple variant t(8;21) acute myeloid leu
✍ Sylvie Taviaux; Véronique Brunel; Madeleine Dupont; Francisca Fernandez; Concepc 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

We report on the molecular characterization of two acute myeloid leukemias (AML), one AML-M1 (patient 1) and one AML-M2 (patient 2) with t(8;21)(p21;q22) and t(8;20)(q22;p13), respectively, at diagnosis. The locations of the breakpoints, 21q22 in patient 1 and 8q22 in patient 2, prompted us to searc