## Abstract By means of ^3^H thymidine‐labelled adenovirus 2 DNA, adenovirus‐specific DNA sequences have been localized in individual nuclei of adenovirus 2‐ or 12‐infected cells, and adenovirus‐specific RNA sequences have been detected in the permissive cells as well as in cells transformed by ade
In situ hybridization of adenovirus RNA and DNA. II. Detection of adenovirus-specific DNA in transformed and tumour cells
✍ Scribed by A. R. Dunn; P. H. Gallimore; K. W. Jones; J. K. McDougall
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- French
- Weight
- 700 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
The method of in situ molecular hybridization has been used to detect adenovirus DNA in permissively and non‐permissively infected cells. Onset of viral DNA synthesis can be detected by this method in individual cells by 12 h after infection. Viral nucleic acid hybrids have been detected at the cytological level in adenovirus‐transformed and tumour cells.
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