𝔖 Bobbio Scriptorium
✦   LIBER   ✦

In situ hybridization: Medical applications


Book ID
123301190
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
52 KB
Volume
47
Category
Article
ISSN
0753-3322

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In situ hybridization (ISH) combines molecular biological techniques with histological and cytological analysis of gene expression. RNA and DNA can be readily localized in specific cells with this method. ISH has been useful as a research tool, and recent studies have used this technique in the diag

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In situ hybridization (ISH) is a technique by which specific nucleotide sequences are identified in cells or tissue sections. These may be endogenous, bacterial or viral, DNA or RNA. On the basis of research applications, the technique is now being translated into diagnostic practice, mainly in the