Applications of in situ hybridization to muscle embryology
✍ Scribed by F. Fougerousae; M. Durand; L. Suel; N. Roméro; M. Abitbol; J. Beckmann
- Book ID
- 116168902
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 118 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0960-8966
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In situ hybridization (ISH) combines molecular biological techniques with histological and cytological analysis of gene expression. RNA and DNA can be readily localized in specific cells with this method. ISH has been useful as a research tool, and recent studies have used this technique in the diag
We compared the distribution of deleted mitochondrial DNA (⌬-mtDNA) in skeletal muscle of a patient with autosomal recessive (AR) and another with autosomal dominant (AD) progressive external ophthalmoplegia (PEO) by in situ hybridization (ISH). The patients studied had similar numbers of fibers def
In situ hybridization (ISH) is a technique by which specific nucleotide sequences are identified in cells or tissue sections. These may be endogenous, bacterial or viral, DNA or RNA. On the basis of research applications, the technique is now being translated into diagnostic practice, mainly in the