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In silico identification of viper phospholipaseA2 inhibitors: validation by in vitro, in vivo studies

✍ Scribed by Amit Nargotra; Sujata Sharma; Mohd Iqbal Alam; Zabeer Ahmed; Asha Bhagat; Subhash Chander Taneja; Ghulam Nabi Qazi; Surrinder Koul


Book ID
106240525
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
533 KB
Volume
17
Category
Article
ISSN
1610-2940

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Interleukin-1b-converting enzyme (ICE) is a cysteine protease responsible for proteolytic activation of the biologically inactive interleukin-1b precursor to the proinflammatory cytokine. ICE and homologous proteases also appear to mediate intracellular protein degradation during programmed cell dea