In- or In(I)-Employed Tailoring of the Stereogenic Centers in the Reformatsky-Type Reactions of Simple Ketones, α-Alkoxy Ketones, and β-Keto Esters.
✍ Scribed by Srinivasarao Arulananda Babu; Makoto Yasuda; Ikuya Shibata; Akio Baba
- Book ID
- 101984470
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 38 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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Reformatsky-Type Addition of Esters of α-Halogeno Carboxylic Acids to Aldehydes and Ketones in the Presence of Fe(CO) 5 . -Fe(CO) 5 -promoted Reformatsky-type addition of α-halogenocarboxylates to carbonyl compounds affords the corresponding β-hydroxycarboxylates (III) (12 examples) in moderate to