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Improved synthetic method for preparing spiro α-chloroepoxides

✍ Scribed by Ken-ichi Sato; Takao Sekiguchi; Tetsuya Hozumi; Toshiya Yamazaki; Shoji Akai

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
80 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis

A new synthetic method via a-chloroolefine derivatives for preparing epimers of spiro a-chloroepoxides (2-chlorooxyrane derivatives), which are useful key intermediates for the synthesis of branched-chain functionalized compounds, is developed as an alternative to previous methods requiring dichloromethyllithium.

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