An improved method for preparing tritium
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Richard S. P. Hsi; Wayne T. Stolle
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Article
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1996
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John Wiley and Sons
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French
โ 122 KB
๐ 2 views
Palladium-on-charcoal catalyzed reduction of N-methyl-3-(3-bromo)phenyl-3-(4-trifluoromethyl)phenoxypropylamine (1) with tritium gas produces a mixture of the debrominated product [3H]fluoxetine (2) and N-methyl-3-[3-3Hlphenylpropylamine(3), which results from cleavage of the benzylic carbon-oxygen