Improved Sensitivity in Selective NMR Correlation Spectroscopy and Applications to the Determination of Scalar Couplings in Peptides and Proteins
β Scribed by Borgnat, Pierre; Lesage, Anne; Caldarelli, Stefano; Emsley, Lyndon
- Book ID
- 126177224
- Publisher
- American Chemical Society
- Year
- 1996
- Tongue
- English
- Weight
- 185 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
Several existing methods permit measurement of the torsion angles Ο, Ο and Ο in peptides and proteins with solid-state MAS NMR experiments. Currently, however, there is not an approach that is applicable to measurement of Ο in the angular range -20 β’ to -70 β’ , commonly found in Ξ±-helical structures
## Abstract Several new protonβdetected heteronuclear twoβdimensional (2D) nmr techniques are presented that exhibit the features of __selection__ and __editing__ of multiplicity. The theoretical basis of the new features is briefly discussed and the application of the 2D techniques to a thioanalog
## Abstract The Ο angle in a cyclic peptide is determined by the combined use of homonuclear and heteronuclear coupling constants. Two of the four coupling constants that define the Ο angle in a peptide are determined exactly, two qualitatively. Via Karplusβtype equations, they are transformed into