A proton-detected heteronuclear 'H-"P correlation experiment that uses z-pulsed field gradients to select coherences and suppress spectral artefacts is demonstrated for [d(G,T,G,)] 2 , an oligonucleotide which forms a 7 kDa DNA quadruplex in the presence of Na+ and displays considerable spectral ove
Improved Pulse Program for Long-Range Heteronuclear Correlation
β Scribed by R.E. Hoffman; A. Weitz; M. Rabinovitz
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 415 KB
- Volume
- 102
- Category
- Article
- ISSN
- 1064-1858
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A modified long-range heteronuclear chemical shift correlation pulse sequence which eliminates modulations of response intensity due to one-bond proton-carbon I'J(CH)] spin couplings is described. The 'decoupling' of one-bond modulation has been accomplished through the use of a bilinear rotational