## Abstract A new synthetic approach for the production of isoquinuclidine 6 from dipentene (__rac__βlimonene, 1) is described. The nitroxyl 5, a rigid analogue of TEMPO, has been prepared from 6 in 87% yield.
Improved method for preparing 3-azabicyclo[3.2.1]octane hydrochloride and the synthesis of its phenothiazine derivatives
β Scribed by N. D. Potti; W. Lewis Nobles
- Publisher
- John Wiley and Sons
- Year
- 1968
- Tongue
- English
- Weight
- 268 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0022-3549
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A series of 1-azabicyclo[2.2.2]octan-3-one oximes and related 1-azabicyclo-[2.2.2]-octan-3-one hydroxylamines were synthesized and tested for muscarinic M3 activity. All compounds showed at least some muscarinic binding properties, however, only one member of the series demonstrated mucarinic M3 ago
Some amides (1a-7a and 1b-7b) derived from 3-methyl-3-azabicyclo[3.2.1]octan-8a(b)-amines were synthesized and studied by IR, 1 H and 13 C NMR spectroscopies. The assignment of all carbon and protons resonances was achieved through the application of one dimensional selective NOE and two dimensional
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