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Improved membrane protein topology prediction by domain assignments

✍ Scribed by Andreas Bernsel; Gunnar Von Heijne


Book ID
111752470
Publisher
Cold Spring Harbor Laboratory Press
Year
2005
Tongue
English
Weight
134 KB
Volume
14
Category
Article
ISSN
0961-8368

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Topology prediction of membrane proteins
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## Abstract A new method is described for prediction of protein membrane topology (intra‐ and extracellular sidedness) from multiply aligned amino acid sequences after determination of the membrane‐spanning segments. The prediction technique relies on residue compositional differences in the protei