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Reliability Measures for Membrane Protein Topology Prediction Algorithms

✍ Scribed by Karin Melén; Anders Krogh; Gunnar von Heijne

Book ID
117143261
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
291 KB
Volume
327
Category
Article
ISSN
0022-2836

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## Abstract A new method is described for prediction of protein membrane topology (intra‐ and extracellular sidedness) from multiply aligned amino acid sequences after determination of the membrane‐spanning segments. The prediction technique relies on residue compositional differences in the protei