Improved intestinal absorption of a poorly water-soluble oral drug using mannitol microparticles containing a nanosolid drug dispersion
โ Scribed by Yukiko Nishino; Aya Kubota; Takanori Kanazawa; Yuuki Takashima; Tetsuya Ozeki; Hiroaki Okada
- Book ID
- 112134686
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 422 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
L-365 260, a specific and potent nonpeptide antagonist of the CCK, receptor, is under investigation for its potential utility in the treatment of anxiety and panic disorders. This drug has a very low aqueous solubility (<2lgmL-'). When L-365 260 was given orally as a suspension in 0.5% methylcellulo
Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. This work addresses the latest techniques and materials to overcome these hurdles, providing a thorough review of current formulation stra