๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Drug Delivery Strategies for Poorly Water-Soluble Drugs (Douroumis/Drug) || Hot Melt Extrusion: A Process Overview and Use in Manufacturing Solid Dispersions of Poorly Water-Soluble Drugs

โœ Scribed by Douroumis, Dennis; Fahr, Alfred

Book ID
120334872
Publisher
John Wiley & Sons Ltd
Year
2013
Tongue
English
Weight
271 KB
Edition
1
Category
Article
ISBN
0470711973

No coin nor oath required. For personal study only.

โœฆ Synopsis

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. This work addresses the latest techniques and materials to overcome these hurdles, providing a thorough review of current formulation strategies for a wide range of hydrophobic drugs. With a focus on critical formulation features and clinical studies, the book covers instrumentation, operation principles, applications, scale-up considerations, regulatory issues, and more. An essential guide for researchers in drug delivery, polymers, and biomaterials.

๐Ÿ“œ SIMILAR VOLUMES

Drug Delivery Strategies for Poorly Wate
Drug Delivery Strategies for Poorly Water-Soluble Drugs (Douroumis/Drug) || Micro- and Nanosizing of Poorly Soluble Drugs by Grinding Techniques
โœ Douroumis, Dennis; Fahr, Alfred ๐Ÿ“‚ Article ๐Ÿ“… 2013 ๐Ÿ› John Wiley & Sons Ltd ๐ŸŒ English โš– 410 KB

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. This work addresses the latest techniques and materials to overcome these hurdles, providing a thorough review of current formulation stra

Development of clinical dosage forms for
Development of clinical dosage forms for a poorly water-soluble drug II: Formulation and characterization of a novel solid microemulsion preconcentrate system for oral delivery of a poorly water-soluble drug
โœ Ping Li; Sara R. Hynes; Thomas F. Haefele; Madhu Pudipeddi; Alan E. Royce; Abu T ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 706 KB

The solution of a poorly water-soluble drug in a liquid lipid-surfactant mixture, which served as a microemulsion preconcentrate, was converted into a solid form by incorporating it in a solid polyethylene glycol (PEG) matrix. The solid microemulsion preconcentrates thus formed consisted of Capmul P