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Improved Auxiliary for the Synthesis of Medium-Sized Bis(lactams)

✍ Scribed by Jasper Springer; T. Paul Jansen; Steen Ingemann; Henk Hiemstra; Jan H. van Maarseveen

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
177 KB
Volume
2008
Category
Article
ISSN
1434-193X

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ChemInform Abstract: Synthesis of Small
ChemInform Abstract: Synthesis of Small and Medium Sized 2,2-Disubstituted Lactams via the β€œ Intramolecular” Three Component Ugi Reaction.
✍ G. C. B. HARRIMAN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

Synthesis of Small and Medium Sized 2,2-Disubstituted Lactams via the " Intramolecular" Three Component Ugi Reaction. -Tethered keto-acids undergo an intramolecular three-component Ugi reaction with a variety of primary amines and isocyanates to form five-to eight-membered lactams in good yields. -(