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Synthesis of the First Penicillin Derivatives with Medium-Sized Lactam Ring and of Related Thiazolidines

✍ Scribed by Peter Imming


Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
869 KB
Volume
328
Category
Article
ISSN
0365-6233

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Starting from siloxycyclopropyl-substituted dimethyl derivatives 11, 12, 13, cycloeicosanone derivative 16, cyclotetradecanone derivative 19 and cyclononane malonates 1 and 2 a chain elongation was performed to give new malonates 8, 9, 10, and 18 in reasonable overall yield. derivative 22 (together