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Impromidine is a partial histamine H2-receptor agonist on human ventricular myocardium

โœ Scribed by T.A.H. English; R.W. Gristwood; D.A.A. Owen; J. Wallwork

Book ID
117958494
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
680 KB
Volume
89
Category
Article
ISSN
0007-1188

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Short-term toxicological studies with impromidine (SK&F 92676): A specific histamine H2-receptor agonist
โœ G. B. Leslie; D. A. A. Owen; Frances D. Pollitt; T. J. Sutton; T. F. Walker ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 467 KB

## Abstract Impromidine is a specific, potent histamine H~2~โ€receptor agonist. The present paper describes the results of acute and shortโ€term repeatedโ€dose toxicity studies with impromidine in rodents and dogs. The intravenous LD~50~ was 9.6 mg kg^โˆ’1^ in male mice, 12.7 mg kg^โˆ’1^ in female mice an