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A comparative study with impromidine (SKF 92676), a potent agonist for histamine H2-receptors

✍ Scribed by H. E. Aksulu; Z. S. Ercan; R. K. Türker

Publisher
SP Birkhäuser Verlag Basel
Year
1979
Tongue
English
Weight
455 KB
Volume
9
Category
Article
ISSN
1420-908X

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Short-term toxicological studies with impromidine (SK&F 92676): A specific histamine H2-receptor agonist
✍ G. B. Leslie; D. A. A. Owen; Frances D. Pollitt; T. J. Sutton; T. F. Walker 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 467 KB

## Abstract Impromidine is a specific, potent histamine H~2~‐receptor agonist. The present paper describes the results of acute and short‐term repeated‐dose toxicity studies with impromidine in rodents and dogs. The intravenous LD~50~ was 9.6 mg kg^−1^ in male mice, 12.7 mg kg^−1^ in female mice an