Importance of measuring products of non-enzymatic glycation of proteins
β Scribed by Annunziata Lapolla; Pietro Traldi; Domenico Fedele
- Book ID
- 108095272
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 715 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0009-9120
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Among postβtranslational modifications of proteins, nonβenzymatic glycation is one of the less frequently studied by experts in proteomics. However, the relevance of protein glycation has been widely shown up in several pathological conditions. In fact, nonβenzymatic glycation has been
2-(ZFuroyl)-~2-furanyl)-l~-imidazole (FFI) is detected in total histones and the lysine-rich histone 1 fraction isolated from calf thymus after in vitro glycation and hydrolysis with HCl, using gas chromatogaphic/mass spectrometric analysis. The finding suggests that glucose is bound to the &-amino