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Implementation of a Process Analytical Technology System in a Freeze-Drying Process Using Raman Spectroscopy for In-Line Process Monitoring

✍ Scribed by De Beer, T. R. M.; Allesø, M.; Goethals, F.; Coppens, A.; Vander Heyden, Y.; Lopez De Diego, H.; Rantanen, J.; Verpoort, F.; Vervaet, C.; Remon, J. P.; Baeyens, W. R. G.


Book ID
120584066
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
249 KB
Volume
79
Category
Article
ISSN
0003-2700

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In-line and real-time process monitoring
✍ De Beer, T. R.M. (author);Vercruysse, P. (author);Burggraeve, A. (author);Quinte 📂 Article 📅 2009 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 755 KB

The aim of the present study was to examine the complementary properties of Raman and near infrared (NIR) spectroscopy as PAT tools for the fast, noninvasive, nondestructive and in-line process monitoring of a freeze drying process. Therefore, Raman and NIR probes were built in the freeze dryer cham