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In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools

✍ Scribed by De Beer, T. R.M. (author);Vercruysse, P. (author);Burggraeve, A. (author);Quinten, T. (author);Ouyang, J. (author);Zhang, X. (author);Vervaet, C. (author);Remon, J. P. (author);Baeyens, W. R.G. (author)

Publisher: John Wiley and Sons Inc.
Year: 2009
Tongue: English
Weight: 755 KB
Volume: 98
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.21633

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In-line and real-time process monitoring

In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools

✍ De Beer, T. R.M. (author);Vercruysse, P. (author);Burggraeve, A. (author);Quinte 📂 Article 📅 2009 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 755 KB

The aim of the present study was to examine the complementary properties of Raman and near infrared (NIR) spectroscopy as PAT tools for the fast, noninvasive, nondestructive and in-line process monitoring of a freeze drying process. Therefore, Raman and NIR probes were built in the freeze dryer cham