Antigen-specific Treg impair CD8+ T-cell
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Pascal Chappert; Marylène Leboeuf; Philippe Rameau; Mélanie Lalfer; Sabine Desbo
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Article
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2010
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John Wiley and Sons
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English
β 519 KB
## Abstract Foxp3^+^ Treg are crucial for the maintenance of selfβtolerance and have been shown to control CD8^+^ Tβcell effector functions. In addition, Treg are thought to control the priming of CD8^+^ T cells, which recognize the same antigens as Treg. Taking advantage of our model of peripheral