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Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand

✍ Scribed by Grewal, Iqbal S.; Xu, Jianchao; Flavell, Richard A.


Book ID
109794687
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
693 KB
Volume
378
Category
Article
ISSN
0028-0836

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## Abstract Foxp3^+^ Treg are crucial for the maintenance of self‐tolerance and have been shown to control CD8^+^ T‐cell effector functions. In addition, Treg are thought to control the priming of CD8^+^ T cells, which recognize the same antigens as Treg. Taking advantage of our model of peripheral