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Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells

โœ Scribed by Uhl, M; Kepp, O; Jusforgues-Saklani, H; Vicencio, J-M; Kroemer, G; Albert, M L


Book ID
109842315
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
403 KB
Volume
16
Category
Article
ISSN
1350-9047

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## Abstract Dendritic cells (DC) generated after a shortโ€term exposure of monocytes to IFNโ€ฮฑ and GMโ€CSF (IFNโ€DC) are highly effective in inducing crossโ€priming of CD8^+^ T cells against viral antigens. We have investigated the mechanisms responsible for the special attitude of these DC and compared