Inhibition of CD40 expression and CD40-m
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Michael R. Shurin; Zoya R. Yurkovetsky; Irina L. Tourkova; Levent Balkir; Galina
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Article
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2002
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John Wiley and Sons
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French
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As CD40 plays a key role in both antitumor immunity and DC maturation, we have studied the regulation of its expression during DC hematopoiesis (dendropoiesis) in vitro and in vivo in the tumor microenvironment. Using MC38 colon adenocarcinoma tumor models, we have demonstrated that DCs generated in