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Antigen processing and CD24 expression determine antigen presentation by splenic CD4+ and CD8+ dendritic cells

✍ Scribed by David Askew; Clifford V. Harding

Book ID: 108782201
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 369 KB
Volume: 123
Category: Article
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.2007.02711.x

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## Abstract Resident CD8^+^ DCs perform several functions, including cross‐presenting antigen and rapidly engulfing the Gram‐positive intracellular pathogen __Listeria monocytogenes__. Little is known about how these functions of CD8^+^ DCs are modulated. Here, we show that granulocyte‐macrophage C