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Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cells

✍ Scribed by Irina L. Tourkova; Galina V. Shurin; Soldano Ferrone; Michael R. Shurin


Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
379 KB
Volume
58
Category
Article
ISSN
0340-7004

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## Abstract Here we have studied the effects of apoptotic cell death induced by chemotherapic agents on tumor phagocytosis by dendritic cells (DC) and presentation of the relevant antigen to T lymphocytes. Annexin‐V‐FITC (Ann‐V) and propidium iodide (PI) staining was used to assess early apoptotic