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Impact of polymers on lipid cationic mediated gene transfer

✍ Scribed by R. Chèvre; E. Letrou-Bonneval; R. Labas; F. Beilvert; B. Pitard


Book ID
118642131
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
62 KB
Volume
8
Category
Article
ISSN
1569-1993

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## Abstract ## Background The weak efficiency of plasmid transfer into the cytosol remains one of the major limiting factors to achieve an efficient transfection with DNA/cationic polymer complexes. We found that divalent metal Zn^2+^ can improve the polyfection efficiency, especially with DNA/his