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The role of non-ionic surfactants on cationic lipid mediated gene transfer

✍ Scribed by Tae Woo Kim; Young Jin Kim; Hesson Chung; Ick Chan Kwon; Ha Chin Sung; Seo Young Jeong

Book ID
114161778
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
597 KB
Volume
82
Category
Article
ISSN
0168-3659

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## Background: Cationic lipid-mediated gene transfer is a promising approach for gene therapy. however, despite the significant amount of lipoplexes internalized by target cells, transgene expression remains too low. obstacles to nuclear accumulation of plasmid dna include: the passage of dna acros