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Cationic lipid-mediated gene transfer to the growing murine and human airway

✍ Scribed by Jaffé, A; Judd, D; Ratcliffe, C; Cheng, S H; Bush, A; Geddes, D M; Alton, E W F W


Book ID
110038590
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
168 KB
Volume
7
Category
Article
ISSN
0969-7128

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## Background: Cationic lipid-mediated gene transfer is a promising approach for gene therapy. however, despite the significant amount of lipoplexes internalized by target cells, transgene expression remains too low. obstacles to nuclear accumulation of plasmid dna include: the passage of dna acros