## Abstract The extracellular matrix (ECM) represents a major barrier for delivery of therapeutic drugs, and the transport is determined by the ECM composition, structure, and distribution. Because of the high interstitial fluid pressure in tumors, diffusion becomes the main transport mechanism thr
Impact of Physical Boundaries on the Mechanics of Collagen Gels and Mechanosensation
โ Scribed by Mohammadi, Hamid; McCulloch, Christopher
- Book ID
- 122399582
- Publisher
- Biophysical Society
- Year
- 2014
- Tongue
- English
- Weight
- 37 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0006-3495
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## Abstract Collagen gels provide a biocompatible matrix for replacing soft tissues, but it is essential to determine whether the mechanical properties of the matrix can be retained after cell ingrowth into the collagen scaffold. We have determined the mechanical strength of four collagen gel compo
Collagen solutions (0.25% w/v) were polymer-side illumination of the gels revealed the more granular apized in microgravity (STS-77, 10 days) along with simultane-pearance of the ground gels relative to the highly uniform ous ground controls. Assembly conditions were achieved by appearance of the fl