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Impact of P-Glycoprotein on Blood–Retinal Barrier Permeability: Comparison of Blood–Aqueous Humor and Blood–Brain Barrier Using Mdr1a Knockout Rats

✍ Scribed by Fujii, Shinobu; Setoguchi, Chikako; Kawazu, Kouichi; Hosoya, Ken-ichi


Book ID
126572773
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Year
2014
Weight
597 KB
Volume
55
Category
Article
ISSN
1552-5783

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## Abstract Two recently published methods of blood‐brain barrier permeability measurement using Gd‐DTPA scanning are compared by authors representing each group. The physiological models are reconciled. Results from both groups agree. These show that the transfer constant (the permeability surface