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Impact of CYP2D6 polymorphism on tamoxifen therapy: where are we?

✍ Scribed by Ariana E. Huber-Wechselberger PhD, Paul Niedetzky MD, Irene Aigner, Elisabeth Haschke-Becher MD

Book ID
113059594
Publisher
Springer Vienna
Year
2012
Tongue
German
Weight
891 KB
Volume
162
Category
Article
ISSN
0043-5341

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CYP2D6 polymorphisms and the impact on t
CYP2D6 polymorphisms and the impact on tamoxifen therapy
✍ Jacob N. Beverage; Tristan M. Sissung; Amy M. Sion; Romano Danesi; William D. Fi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 122 KB

The cytochrome P450 2D6 (CYP2D6) is an enzyme known to metabolize a variety of xenobiotics and drugs. Inter-individual variation in the metabolic capacity of this enzyme has been extensively studied and associations with genotype have been established. Genetic polymorphisms have been grouped as nonf