Deletion and insertion in vivo somatic m
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Karolyn J. Burkhart-Schultz; Irene M. Jones
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Article
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1997
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John Wiley and Sons
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English
β 117 KB
π 2 views
Deletion and insertion mutations have been found to be a major component of the in vivo somatic mutation spectrum in the hypoxanthine phosphoribosyltransferase (hprt) gene of T-lymphocytes. In a population of 172 healthy people (average age, 34; mutant frequency, 10.3 x 10(-6)), deletion/insertion m