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Immunoscintigraphy with biosynthetically-labeled 75Se-antibodies—I. Biodistribution of 75Se-monoclonal antibodies and of free radionuclide

✍ Scribed by Ryser, Jean-Etienne; Carrel, Stefan; Buchegger, Franz; Donath, Alfred

Book ID
123190739
Publisher
Elsevier Science
Year
1990
Weight
1023 KB
Volume
17
Category
Article
ISSN
0883-2897

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## Abstract Carbonic anhydrase IX (CA IX) is frequently expressed in human carcinomas and absent from the corresponding normal tissues. Strong induction by tumor hypoxia predisposes CA IX to serve as a target for cancer diagnostics and therapy. Here we evaluated targeting properties and pharmacokin