𝔖 Bobbio Scriptorium
✦   LIBER   ✦

125I-labelling of an internally 75Se-labelled monoclonal antibody—Biodistribution in tumour-bearing nude mice

✍ Scribed by Grétarsdóttir, Jakobína; Aronsson, Eva Forssell; Jacobsson, Lars; Hafsteinsdóttir, Ólöf; Holmberg, Stig; Hafström, Larsolof; Lindegren, Sture; Karlsson, Börje; Lindholm, Leif; Mattsson, Sören

Book ID
122430743
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
532 KB
Volume
21
Category
Article
ISSN
0969-8051

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Biodistribution of iodine-125 labeled mo
Biodistribution of iodine-125 labeled monoclonal antibody/Interleukin-2 immunoconjugate in athymic mice bearing human tumor xenografts
✍ Kayoko Nakamura; Atsushi Kubo 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB

## Background: Some vasoactive drugs have been studied in the hope of altering the vascular permeability and/or blood of tumors to enhance monoclonal antibody (moab) uptake. the pretreatment of interleukin-2 (il-2), one of the vasoactive reagents, produced a generalized vascular permeability, but i

Biodistribution and pharmacokinetics of
Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia, in nude mice xenografted with human colorectal carcinoma
✍ Adrián Chrastina; Jan Závada; Seppo Parkkila; Štefan Kaluz; Milota Kaluzová; Júl 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 417 KB

## Abstract Carbonic anhydrase IX (CA IX) is frequently expressed in human carcinomas and absent from the corresponding normal tissues. Strong induction by tumor hypoxia predisposes CA IX to serve as a target for cancer diagnostics and therapy. Here we evaluated targeting properties and pharmacokin

Preparation and quality control of 211At
Preparation and quality control of 211At-labelled and 125I-labelled monoclonal antibodies. Biodistribution in mice carrying human osteosarcoma xenografts
✍ Roy H. Larsen; Per Hoff; Jorolf Alstad; Øyvind S. Bruland 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 439 KB

## Abstract Two anti‐osteosarcoma monoclonal antibodies (TP‐3 IgG and TP‐1 F(ab′)~2~) were labelled with the α‐particle emitting radionuclide ^211^At and, for comparison of stability, with ^125^I using the N‐succinimidyl‐3‐(trimethylstannyl)benzoate intermediate. The quality of the final preparatio