Immunoregulatory function of T8 and T4 cells from synovial fluid of patients with chronic arthritis
✍ Scribed by E. Nilsson; L. -V. von Stedingk; G. Biberfeld
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1986
- Tongue
- English
- Weight
- 158 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Rheumatoid arthritis is a T cell-mediated autoimmune disease. The lack of knowledge of the involved target antigens severely hampers research on relevant T cells in patients. Here we describe the functional analysis of freshly isolated T cells from the peripheral blood and the site of the lesion (sy
## Abstract Markedly elevated levels of T cells expressing Ia antigens were found in the synovial membranes and synovial fluids of patients with rheumatoid arthritis. The primary increase in expression of the la antigens was on the OKT 8+ (suppressor/cytotoxic) T cell subset. In addition, the total