The immunomodulatory activity of aqueous extract from Achyrocline satureioides, prepared using heating, was investigated with a mitogen-induced cell proliferation assay and IL-2 secretion in BALB/c mice. The results showed a slightly immunosuppressive activity.
Immunomodulatory activities of Trichilia glabra leaf aqueous extracts
✍ Scribed by Fabián Benencia; Félix C. Coulombié
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 105 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0951-418X
No coin nor oath required. For personal study only.
✦ Synopsis
Human peripheral blood monocytes and polymorphonuclear leukocytes treated with leaf aqueous extracts of the Meliaceae tree Trichilia glabra showed a diminution in both their phagocytic and respiratory burst activities. A decrease in the haemolytic capacity of the human complement was also observed.
The significance of the inhibitory effect observed over some components of the human immune system closely related with the inflammatory process is discussed.
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