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Immunological abnormalities in splenic marginal zone cell lymphoma

โœ Scribed by Murakami, Hirokazu; Irisawa, Hiroyuki; Saitoh, Takayuki; Matsushima, Takafumi; Tamura, Jun'ichi; Sawamura, Morio; Karasawa, Masamitsu; Hosomura, Yasuo; Kojima, Masaru

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
888 KB
Volume
56
Category
Article
ISSN
0361-8609

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โœฆ Synopsis

The clinical features of patients with splenic marginal zone cell lymphoma (SMZCL) have rarely been reported. In the present study, immunological abnormalities, particularly hematological abnormalities, observed in SMZCL were described. Autoimmune hemolytic anemia, immune thrombocytopenia, and appearance of lupus anticoagulant were observed in 2 of 3 patients with SMZCL. Other abnormal data including monoclonal gammopathy and cold agglutinin were also observed in 2 of the 3 patients. Immunological abnormalities may be characteristic complications in patients with SMZCL and must be followed carefully, since they may be a reliable marker of this type of lymphoma activity.

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