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Rituximab monotherapy is highly effective in splenic marginal zone lymphoma

โœ Scribed by Michael Bennett; Shaiy Yegena; Harish P. Dave; Geraldine P. Schechter


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
45 KB
Volume
26
Category
Article
ISSN
0278-0232

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## Abstract Splenectomy has traditionally been considered as a standard first line treatment for splenic marginal zone lymphoma (SMZL) conferring a survival advantage over chemotherapy. However it carries significant complications, especially in elderly patients. The purpose of this retrospective s

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It has been suggested that lymphocytes of mucosa-associated lymphoid tissue (MALT) arise from marginal zone cells and that MALT-derived lymphomas may spread to other extra-nodal sites by homing to marginal zones in different tissues.' Marginal zone expansion has been observed in spleens removed duri