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Immunohistochemical localization of amyloid β-protein with amino-terminal aspartate in the cerebral cortex of patients with Alzheimer's disease

✍ Scribed by Tetsuaki Arai; Haruhiko Akiyama; Kenji Ikeda; Hiromi Kondo; Hiroshi Mori


Book ID
114004666
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
603 KB
Volume
823
Category
Article
ISSN
0006-8993

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Diffuse amyloid beta-protein (Abeta) deposits with numerous glial cells containing C-terminal Abeta fragments occur in the cerebral cortex of patients with Alzheimer's disease. By using a panel of antibodies specific for various epitopes in the Abeta peptide, we have investigated the immunohistochem