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Immunohistochemical expression of p53 and MDM2 within head and neck squamous cell carcinoma

✍ Scribed by S. Tandon; H. Beer; T.M. Jones; M. Birchall; M. Boyd; T.R. Helliwell


Book ID
111390932
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
43 KB
Volume
31
Category
Article
ISSN
1749-4478

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Mutation of the p53 tumor suppressor gene has been demonstrated in a large proportion of human head and neck squamous cell carcinomas (HNSCCs) and has been assumed to play a role in the pathogenesis of these tumors, although no formal evidence of functional aberration has been demonstrated. In this