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Immunofluorescent labeling of increased calpain expression and neuronal death in the spinal cord of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice

✍ Scribed by Bhisham Chera; Kurt E. Schaecher; Anne Rocchini; Syed Z. Imam; Eric A. Sribnick; Swapan K. Ray; Syed F. Ali; Naren L. Banik

Book ID: 113499517
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 425 KB
Volume: 1006
Category: Article
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2004.01.065

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## Abstract Microglia play an important role in the inflammatory process that occurs in Parkinson's disease (PD). Activated microglia produce cytokines and neurotrophins and may have neurotoxic or neurotrophic effects. Because microglia are most proliferative and easily activated during the neonata