Immunoexpression of SALL4 in Wilms Tumors and Developing Kidney
β Scribed by Jeremy Deisch; Jack Raisanen; Dinesh Rakheja
- Book ID
- 107636517
- Publisher
- Springer Netherlands
- Year
- 2011
- Tongue
- English
- Weight
- 694 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1219-4956
No coin nor oath required. For personal study only.
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SALL4 is a homologue of the Drosophila homeotic gene spalt, a zinc finger transcription factor, required for inner cell mass proliferation in early embryonic development. It also interacts with other transcription factors to control the development of the anorectal region, kidney, heart, limbs, and
Thymosins p4 and plo are 2 structurally related polypeptides originally defined in the rat immune system. To date, no truly unambiguous functions have been formally ascribed to these small (<4.9 kDa) acidic proteins. Previous research has demonstrated relationships between expression of these genes