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Analysis of native WT1 protein from frozen human kidney and Wilms' tumors

✍ Scribed by Iben, Sebastian; Royer-Pokora, Brigitte


Book ID
110062054
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
117 KB
Volume
18
Category
Article
ISSN
0950-9232

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## Abstract The Wilms' tumor 1 gene, __WT1__, encodes a zinc‐finger protein that is implicated in the development of Wilms' tumor. Mutant or aberrantly expressed WT1 isoforms have also been described in desmoplastic small round cell tumor, acute leukemias, mesothelioma, breast tumors and melanoma.