Transforming growth factor-beta (TGF-P) is a polypeptide with multiple physiological functions. lsoforms of this growth factor have important roles in control of the cell cycle, in regulation of cell-cell interactions and in growth and development. Malignant transformation has been shown to be assoc
Immunodetection and quantitation of the two forms of transforming growth factor-beta (TGF-β1 and TGF-β2) secreted by cells in culture
✍ Scribed by David Danielpour; Linda L. Dart; Kathleen C. Flanders; Anita B. Roberts; Michael B. Sporn
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 861 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0021-9541
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Regeneration involves a number of cellular processes: revascularisation, invasion by haemopoietic cells, removal of necrotic tissue and finally reformation of the tissues. These processes have been extensively studied in vitro and are known to be affected by various growth factors. However, it has p
A panel of 6 human glioma cell lines was examined for TGF-1 responsiveness. U-178 MG and U-251 MG AgCl1 were significantly inhibited by TGF-1, while U-343 MGa 31L and U-343 MGa 35L were potently stimulated to proliferate. TGF-1 induced endogenous PAI-1 protein synthesis, Smad binding element/(CAG
## Abstract Follistatin‐related gene (FLRG) is a member of the follistatin family of proteins and interacts with transforming growth factor (TGF) superfamily proteins like follistatin. To understand the expression level of FLRG in brain tissue, we examined whether primary neurons and glial cells fr
The pathogenesis of glornerular scarring i s multifactional; recent evidence suggests that transforming growth factor P (TGFP), a pleiotropic cicatricial mediator, may promote mesangial sclerosis by enhancing the production of extracellular matrix proteins. We studied the effect of TGFPl and TFGP2 o
Recently, the existence of the large latent transforming growth factor  (TGF-) complex, consisting of TGF-, the N-terminal part of its precursor (latency-associated peptide [LAP]), and the latent TGF- binding protein (LTBP), was demonstrated in rat liver parenchymal cells (PC) and stellate cells