✦ LIBER ✦
Matrix protein synthesis by glomerular mesangial cells in culture: Effects of transforming growth factor β (TGFβ) and platelet-derived growth factor (PDGF) on fibronectin and collagen type IV mRNA
✍ Scribed by Gertrud Maria Hänsch; Christof Wagner; Antje Bürger; Wenjie Dong; G. Staehler; Michael Stoeck
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 732 KB
- Volume
- 163
- Category
- Article
- ISSN
- 0021-9541
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✦ Synopsis
The pathogenesis of glornerular scarring i s multifactional; recent evidence suggests that transforming growth factor P (TGFP), a pleiotropic cicatricial mediator, may promote mesangial sclerosis by enhancing the production of extracellular matrix proteins. We studied the effect of TGFPl and TFGP2 on collagen type IV