Immunochemical, Structural and Translocating Properties of Anti-DNA Antibodies from (NZB×NZW)F1 Mice
✍ Scribed by Thérèse Ternynck; Alexandre Avrameas; Josiane Ragimbeau; Gérard Buttin; Stratis Avrameas
- Book ID
- 115621587
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 310 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0896-8411
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## Abstract Immunization of NZB and A/J mice against an anti‐DNA hybridoma antibody (F227) derived from (NZB x NZW)F~1~ (B/W) mice allowed the preparation of two anti‐idiotype antisera. These two reagents were shown to recognize different idiotopes of the F227 monoclonal antibody. NZB anti‐idiotypi
## Abstract Anti‐nuclear antibodies could be demonstrated in sero‐negative patients with immune complex glomerulonephritis by means of an acid dissociation method. The antibodies were also found in sero‐negative NZB and (NZB × NZW) F~1~ mice with complex glomerulonephritis. It is suggested that t